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Characterization of Oncolytic Vaccinia Virus Harboring the Human IFNB1 and CES2 Transgenes
PURPOSE: The purpose of this study was to assess characteristics of SJ-815, a novel oncolytic vaccinia virus lacking a functional thymidine kinase-encoding TK gene, and instead, having two human transgenes: the IFNB1 that encodes interferon β1, and the CES2 that encodes carboxylesterase 2, which met...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Cancer Association
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962490/ https://www.ncbi.nlm.nih.gov/pubmed/31401821 http://dx.doi.org/10.4143/crt.2019.161 |