LIN28B Impairs the Transition of hESC-Derived β Cells from the Juvenile to Adult State

Differentiation of human embryonic stem cells into pancreatic β cells holds great promise for the treatment of diabetes. Recent advances have led to the production of glucose-responsive insulin-secreting cells in vitro, but resulting cells remain less mature than their adult primary β cell counterpa...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Xin, Nair, Gopika G., Russ, Holger A., Belair, Cassandra D., Li, Mei-Lan, Shveygert, Mayya, Hebrok, Matthias, Blelloch, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962644/
https://www.ncbi.nlm.nih.gov/pubmed/31883920
http://dx.doi.org/10.1016/j.stemcr.2019.11.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962644/
https://www.ncbi.nlm.nih.gov/pubmed/31883920
http://dx.doi.org/10.1016/j.stemcr.2019.11.009

Ejemplares similares