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LIN28B Impairs the Transition of hESC-Derived β Cells from the Juvenile to Adult State
Differentiation of human embryonic stem cells into pancreatic β cells holds great promise for the treatment of diabetes. Recent advances have led to the production of glucose-responsive insulin-secreting cells in vitro, but resulting cells remain less mature than their adult primary β cell counterpa...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962644/ https://www.ncbi.nlm.nih.gov/pubmed/31883920 http://dx.doi.org/10.1016/j.stemcr.2019.11.009 |