Glucose-6-Phosphate Upregulates Txnip Expression by Interacting With MondoA

The major metabolic fates of glucose in cells are glycolysis and the pentose phosphate pathway, and they share the first step: converting glucose to glucose-6-phosphate (G6P). Here, we show that G6P can be sensed by the transcription factor MondoA/Mlx to modulate Txnip expression. Endogenous knockdo...

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Detalles Bibliográficos
Autores principales: Zhang, Xueyun, Fu, Tao, He, Qian, Gao, Xiang, Luo, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962712/
https://www.ncbi.nlm.nih.gov/pubmed/31993438
http://dx.doi.org/10.3389/fmolb.2019.00147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962712/
https://www.ncbi.nlm.nih.gov/pubmed/31993438
http://dx.doi.org/10.3389/fmolb.2019.00147

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