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Spatial Organization of Proteasome Aggregates in the Regulation of Proteasome Homeostasis

Misfolded proteins and insoluble aggregates are continuously produced in the cell and can result in severe stress that threatens cellular fitness and viability if not managed effectively. Accordingly, organisms have evolved several protective protein quality control (PQC) machineries to address thes...

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Detalles Bibliográficos
Autores principales: Karmon, Ofri, Ben Aroya, Shay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962763/
https://www.ncbi.nlm.nih.gov/pubmed/31998748
http://dx.doi.org/10.3389/fmolb.2019.00150