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Protective Immunity against Canine Distemper Virus in Dogs Induced by Intranasal Immunization with a Recombinant Probiotic Expressing the Viral H Protein

Canine distemper virus (CDV) elicits a severe contagious disease in a broad range of hosts. CDV mortality rates are 50% in domestic dogs and 100% in ferrets. Its primary infection sites are respiratory and intestinal mucosa. This study aimed to develop an effective mucosal CDV vaccine using a non-an...

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Detalles Bibliográficos
Autores principales: Jiang, Yanping, Jia, Shuo, Zheng, Dianzhong, Li, Fengsai, Wang, Shengwen, Wang, Li, Qiao, Xinyuan, Cui, Wen, Tang, Lijie, Xu, Yigang, Xia, Xianzhu, Li, Yijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963260/
https://www.ncbi.nlm.nih.gov/pubmed/31835572
http://dx.doi.org/10.3390/vaccines7040213