Immunogenicity and Protection from Receptor-Binding Domains of Toxins as Potential Vaccine Candidates for Clostridium difficile

The receptor-binding domains (RBDs) located in toxin A and toxin B of Clostridium difficile are known to be nontoxic and immunogenic. We need to develop a new type vaccine based on RBDs. In this study, we expressed and purified recombinant proteins (named RBD-TcdA and RBD-TcdB) as vaccine candidates...

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Detalles Bibliográficos
Autores principales: Luo, Deyan, Liu, Xuechao, Xing, Li, Sun, Yakun, Huang, Jie, Zhang, Liangyan, Li, Jiajia, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963439/
https://www.ncbi.nlm.nih.gov/pubmed/31717334
http://dx.doi.org/10.3390/vaccines7040180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963439/
https://www.ncbi.nlm.nih.gov/pubmed/31717334
http://dx.doi.org/10.3390/vaccines7040180

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