Anti-Tubercular Activity of Substituted 7-Methyl and 7-Formylindolizines and In Silico Study for Prospective Molecular Target Identification

Novel series of diversely substituted indolizines were designed, synthesized, and evaluated for their in vitro anti-mycobacterial activity against H37Rv and multi-drug-resistant (MDR) strains of Mycobacterium tuberculosis (MTB). Many compounds exhibited significant inhibitory activity against MTB H3...

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Detalles Bibliográficos
Autores principales: Venugopala, Katharigatta N., Tratrat, Christophe, Pillay, Melendhran, Mahomoodally, Fawzi M., Bhandary, Subhrajyoti, Chopra, Deepak, Morsy, Mohamed A., Haroun, Michelyne, Aldhubiab, Bandar E., Attimarad, Mahesh, Nair, Anroop B., Sreeharsha, Nagaraja, Venugopala, Rashmi, Chandrashekharappa, Sandeep, Alwassil, Osama I., Odhav, Bharti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963442/
https://www.ncbi.nlm.nih.gov/pubmed/31816928
http://dx.doi.org/10.3390/antibiotics8040247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963442/
https://www.ncbi.nlm.nih.gov/pubmed/31816928
http://dx.doi.org/10.3390/antibiotics8040247

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