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Development of a Novel Pharmaceutical Formula of Nanoparticle Lipid Carriers of Gentamicin/α-Tocopherol and In Vivo Assessment of the Antioxidant Protective Effect of α-Tocopherol in Gentamicin-Induced Nephrotoxicity

Gentamicin is a potent antibiotic with a nephrotoxicity drawback which limits its use. D-α-tocopherol polyethylene glycol succinate (α-tocopherol) is widely used as a surfactant and have potent antioxidant properties. This study aimed to assess the protective effect of α-tocopherol on gentamicin-ind...

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Detalles Bibliográficos
Autores principales: Elfaky, Mahmoud A., Thabit, Abrar K., Sirwi, Alaa, Fahmy, Usama A., Bahabri, Raghdah M., Al-Awad, Eman A., Basaeed, Lamis F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963454/
https://www.ncbi.nlm.nih.gov/pubmed/31775233
http://dx.doi.org/10.3390/antibiotics8040234