MVA-Vectored Pentameric Complex (PC) and gB Vaccines Improve Pregnancy Outcome after Guinea Pig CMV Challenge, but Only gB Vaccine Reduces Vertical Transmission

(1) Background: A congenital cytomegalovirus (cCMV) vaccine is a major research priority, but the essential glycoprotein target(s) remain unclear. We compared CMV gB (gpgB), gH/gL (gp75/gL), and pentameric complex (gpPC, composed of gH/gL/GP129/GP131/GP133) vaccines in a guinea pig CMV (GPCMV) conge...

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Detalles Bibliográficos
Autores principales: Contreras, Heidi, Wussow, Felix, Fernández-Alarcón, Claudia, Bierle, Craig, Nguyen, Jenny, Diamond, Don J., Schleiss, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963609/
https://www.ncbi.nlm.nih.gov/pubmed/31739399
http://dx.doi.org/10.3390/vaccines7040182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963609/
https://www.ncbi.nlm.nih.gov/pubmed/31739399
http://dx.doi.org/10.3390/vaccines7040182

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