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Using Colistin as a Trojan Horse: Inactivation of Gram-Negative Bacteria with Chlorophyllin

Colistin (polymyxin E) is a membrane-destabilizing antibiotic used against Gram-negative bacteria. We have recently reported that the outer membrane prevents the uptake of antibacterial chlorophyllin into Gram-negative cells. In this study, we used sub-toxic concentrations of colistin to weaken this...

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Detalles Bibliográficos
Autores principales: Richter, Peter, Krüger, Marcus, Prasad, Binod, Gastiger, Susanne, Bodenschatz, Mona, Wieder, Florian, Burkovski, Andreas, Geißdörfer, Walter, Lebert, Michael, Strauch, Sebastian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963628/
https://www.ncbi.nlm.nih.gov/pubmed/31547053
http://dx.doi.org/10.3390/antibiotics8040158