Characterization of the Metabolic Response of Streptomyces clavuligerus to Shear Stress in Stirred Tanks and Single-Use 2D Rocking Motion Bioreactors for Clavulanic Acid Production

Streptomyces clavuligerus is a gram-positive filamentous bacterium notable for producing clavulanic acid (CA), an inhibitor of β-lactamase enzymes, which confers resistance to bacteria against several antibiotics. Here we present a comparative analysis of the morphological and metabolic response of...

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Detalles Bibliográficos
Autores principales: Gómez-Ríos, David, Junne, Stefan, Neubauer, Peter, Ochoa, Silvia, Ríos-Estepa, Rigoberto, Ramírez-Malule, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963652/
https://www.ncbi.nlm.nih.gov/pubmed/31569725
http://dx.doi.org/10.3390/antibiotics8040168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963652/
https://www.ncbi.nlm.nih.gov/pubmed/31569725
http://dx.doi.org/10.3390/antibiotics8040168

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