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Kinetic Study of CO(2) Hydration by Small-Molecule Catalysts with A Second Coordination Sphere that Mimic the Effect of the Thr-199 Residue of Carbonic Anhydrase

Zinc complexes were synthesized as catalysts that mimic the ability of carbonic anhydrase (CA) for the CO(2) hydration reaction (H(2)O + CO(2) → H(+) + HCO(3)(−)). For these complexes, a tris(2-pyridylmethyl)amine (TPA) ligand mimicking only the active site, and a 6-((bis(pyridin-2-ylmethyl)amino)me...

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Detalles Bibliográficos
Autores principales: Park, DongKook, Lee, Man Sig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963681/
https://www.ncbi.nlm.nih.gov/pubmed/31581538
http://dx.doi.org/10.3390/biomimetics4040066