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Antibody Structure and Function: The Basis for Engineering Therapeutics

Antibodies and antibody-derived macromolecules have established themselves as the mainstay in protein-based therapeutic molecules (biologics). Our knowledge of the structure–function relationships of antibodies provides a platform for protein engineering that has been exploited to generate a wide ra...

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Detalles Bibliográficos
Autores principales: Chiu, Mark L., Goulet, Dennis R., Teplyakov, Alexey, Gilliland, Gary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963682/
https://www.ncbi.nlm.nih.gov/pubmed/31816964
http://dx.doi.org/10.3390/antib8040055