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Inactivation of Zika Virus by Photoactive Iodonaphthyl Azide Preserves Immunogenic Potential of the Virus

Zika virus’s (ZIKV) emergence as a pathogen of significant public health importance has accelerated efforts to develop a ZIKV vaccine. To date, the need for an effective ZIKV vaccine is unmet. In this study, we report inactivation of ZIKV using a hydrophobic photoactive compound: 1, 5 iodonaphthyl a...

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Detalles Bibliográficos
Autores principales: Austin, Amy L., Galasso, Bianca, Nickens, Caitlin, Knollmann-Ritschel, Barbara, Sharma, Anuj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963691/
https://www.ncbi.nlm.nih.gov/pubmed/31614887
http://dx.doi.org/10.3390/pathogens8040188