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Highly Pathogenic Avian Influenza H5 Hemagglutinin Fused with the A Subunit of Type IIb Escherichia coli Heat Labile Enterotoxin Elicited Protective Immunity and Neutralization by Intranasal Immunization in Mouse and Chicken Models

Highly pathogenic avian influenza viruses are classified by the World Organization for Animal Health (OIE) as causes of devastating avian diseases. This study aimed to develop type IIb Escherichia coli heat-labile enterotoxin (LTIIb) as novel mucosal adjuvants for mucosal vaccine development. The fu...

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Detalles Bibliográficos
Autores principales: Tang, Neos, Lin, Shi-Wei, Chen, Ting-Hsuan, Jan, Jia-Tsrong, Wu, Hung-Yi, Wu, Suh-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963717/
https://www.ncbi.nlm.nih.gov/pubmed/31766677
http://dx.doi.org/10.3390/vaccines7040193