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Meningitic Escherichia coli Induction of ANGPTL4 in Brain Microvascular Endothelial Cells Contributes to Blood–Brain Barrier Disruption via ARHGAP5/RhoA/MYL5 Signaling Cascade

Bacterial meningitis is currently recognized as one of the most important life-threatening infections of the central nervous system (CNS) with high morbidity and mortality, despite the advancements in antimicrobial treatment. The disruption of blood–brain barrier (BBB) induced by meningitis bacteria...

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Detalles Bibliográficos
Autores principales: Liu, Lu, Li, Jixuan, Huo, Dong, Peng, Zhong, Yang, Ruicheng, Fu, Jiyang, Xu, Bojie, Yang, Bo, Chen, Huanchun, Wang, Xiangru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963727/
https://www.ncbi.nlm.nih.gov/pubmed/31766605
http://dx.doi.org/10.3390/pathogens8040254