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Variable Surface Glycoprotein from Trypanosoma brucei Undergoes Cleavage by Matrix Metalloproteinases: An in silico Approach

In order to survive as extracellular parasites in the mammalian host environment, Trypanosoma brucei has developed efficient mechanisms of immune system evasion, which include the abundant expression of a variable surface glycoprotein (VSG) coat. VSGs are anchored in the parasite membrane by covalen...

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Detalles Bibliográficos
Autores principales: Moreno, Cláudia Jassica Gonçalves, Torres, Taffarel, Silva, Marcelo Sousa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963732/
https://www.ncbi.nlm.nih.gov/pubmed/31597256
http://dx.doi.org/10.3390/pathogens8040178