Development of new in vitro models of lung protease activity for investigating stability of inhaled biological therapies and drug delivery systems

Proteases play a vital role in lung health and are critically important to the metabolic clearance of inhaled protein-based therapeutics after inhalation. Surprisingly little is known about lung fluid protease composition and there is a consequent lack of biorelevant experimental models, which limit...

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Detalles Bibliográficos
Autores principales: Woods, Arcadia, Andrian, Teodora, Sharp, Gemma, Bicer, Elif Melis, Vandera, Kalliopi-Kelli A., Patel, Ayasha, Mudway, Ian, Dailey, Lea Ann, Forbes, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963770/
https://www.ncbi.nlm.nih.gov/pubmed/31756380
http://dx.doi.org/10.1016/j.ejpb.2019.11.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963770/
https://www.ncbi.nlm.nih.gov/pubmed/31756380
http://dx.doi.org/10.1016/j.ejpb.2019.11.005

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