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Development of new in vitro models of lung protease activity for investigating stability of inhaled biological therapies and drug delivery systems
Proteases play a vital role in lung health and are critically important to the metabolic clearance of inhaled protein-based therapeutics after inhalation. Surprisingly little is known about lung fluid protease composition and there is a consequent lack of biorelevant experimental models, which limit...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963770/ https://www.ncbi.nlm.nih.gov/pubmed/31756380 http://dx.doi.org/10.1016/j.ejpb.2019.11.005 |