Cargando…

Photocrosslinking Activity-Based Probes for Ubiquitin RING E3 Ligases

Activity-based protein profiling is an invaluable technique for studying enzyme biology and facilitating the development of therapeutics. Ubiquitin E3 ligases (E3s) are one of the largest enzyme families and regulate a host of (patho)physiological processes. The largest subtype are the RING E3s of w...

Descripción completa

Detalles Bibliográficos
Autores principales: Mathur, Sunil, Fletcher, Adam J., Branigan, Emma, Hay, Ronald T., Virdee, Satpal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963778/
https://www.ncbi.nlm.nih.gov/pubmed/31859248
http://dx.doi.org/10.1016/j.chembiol.2019.11.013