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Photocrosslinking Activity-Based Probes for Ubiquitin RING E3 Ligases
Activity-based protein profiling is an invaluable technique for studying enzyme biology and facilitating the development of therapeutics. Ubiquitin E3 ligases (E3s) are one of the largest enzyme families and regulate a host of (patho)physiological processes. The largest subtype are the RING E3s of w...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963778/ https://www.ncbi.nlm.nih.gov/pubmed/31859248 http://dx.doi.org/10.1016/j.chembiol.2019.11.013 |