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Understanding Inter-Individual Variability in Monoclonal Antibody Disposition

Monoclonal antibodies (mAbs) are currently the largest and most dominant class of therapeutic proteins. Inter-individual variability has been observed for several mAbs; however, an understanding of the underlying mechanisms and factors contributing to inter-subject differences in mAb disposition is...

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Detalles Bibliográficos
Autores principales: Thomas, Veena A., Balthasar, Joseph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963779/
https://www.ncbi.nlm.nih.gov/pubmed/31817205
http://dx.doi.org/10.3390/antib8040056