Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment

Although there are many prospective targets in the tumor microenvironment (TME) of high-grade serous ovarian cancer (HGSOC), pre-clinical testing is challenging, especially as there is limited information on the murine TME. Here, we characterize the TME of six orthotopic, transplantable syngeneic mu...

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Detalles Bibliográficos
Autores principales: Maniati, Eleni, Berlato, Chiara, Gopinathan, Ganga, Heath, Owen, Kotantaki, Panoraia, Lakhani, Anissa, McDermott, Jacqueline, Pegrum, Colin, Delaine-Smith, Robin M., Pearce, Oliver M.T., Hirani, Priyanka, Joy, Joash D., Szabova, Ludmila, Perets, Ruth, Sansom, Owen J., Drapkin, Ronny, Bailey, Peter, Balkwill, Frances R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963791/
https://www.ncbi.nlm.nih.gov/pubmed/31940494
http://dx.doi.org/10.1016/j.celrep.2019.12.034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963791/
https://www.ncbi.nlm.nih.gov/pubmed/31940494
http://dx.doi.org/10.1016/j.celrep.2019.12.034

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