Simultaneous Deletion of Virulence Factors and Insertion of Antigens into the Infectious Laryngotracheitis Virus Using NHEJ-CRISPR/Cas9 and Cre–Lox System for Construction of a Stable Vaccine Vector

Infectious laryngotracheitis virus (ILTV) is a promising vaccine vector due to its heterologous gene accommodation capabilities, low pathogenicity, and potential to induce cellular and humoral arms of immunity. Owing to these characteristics, different gene-deletion versions of ILTVs have been succe...

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Detalles Bibliográficos
Autores principales: Atasoy, Mustafa Ozan, Rohaim, Mohammed A., Munir, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963826/
https://www.ncbi.nlm.nih.gov/pubmed/31817447
http://dx.doi.org/10.3390/vaccines7040207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963826/
https://www.ncbi.nlm.nih.gov/pubmed/31817447
http://dx.doi.org/10.3390/vaccines7040207

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