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Hepatitis E Virus Shows More Genomic Alterations in Cell Culture than In Vivo

Hepatitis E Virus (HEV) mutations following ribavirin treatment have been associated with treatment non-response and viral persistence, but spontaneous occurring genomic variations have been less well characterized. We here set out to study the HEV genome composition in 2 patient sample types and 2...

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Detalles Bibliográficos
Autores principales: Sari, Gulce, van de Garde, Martijn D.B., van Schoonhoven, Anne, Voermans, Jolanda J.C., van der Eijk, Annemiek A., de Man, Robert A., Boonstra, Andre, Vanwolleghem, Thomas, Pas, Suzan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963849/
https://www.ncbi.nlm.nih.gov/pubmed/31766624
http://dx.doi.org/10.3390/pathogens8040255