Lipophilic Metabolic Efficiency (LipMetE) and Drug Efficiency Indices to Explore the Metabolic Properties of the Substrates of Selected Cytochrome P450 Isoforms

[Image: see text] Cytochrome P450 (CYP450) enzymes belong to a superfamily of heme-containing proteins that are involved in the metabolism of structurally diverse endogenous and exogenous compounds. Various proof-of-concept studies indicate that metabolic stability and intrinsic clearance of CYP450...

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Detalles Bibliográficos
Autores principales: Kiani, Yusra Sajid, Jabeen, Ishrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963890/
https://www.ncbi.nlm.nih.gov/pubmed/31956764
http://dx.doi.org/10.1021/acsomega.9b02344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963890/
https://www.ncbi.nlm.nih.gov/pubmed/31956764
http://dx.doi.org/10.1021/acsomega.9b02344

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