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The Impact of Immunoglobulin G1 Fc Sialylation on Backbone Amide H/D Exchange

The usefulness of higher-order structural information provided by hydrogen/deuterium exchange-mass spectrometry (H/DX-MS) for the structural impact analyses of chemical and post-translational antibody modifications has been demonstrated in various studies. However, the structure–function assessment...

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Detalles Bibliográficos
Autores principales: Kuhne, Felix, Bonnington, Lea, Malik, Sebastian, Thomann, Marco, Avenal, Cecile, Cymer, Florian, Wegele, Harald, Reusch, Dietmar, Mormann, Michael, Bulau, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963987/
https://www.ncbi.nlm.nih.gov/pubmed/31581521
http://dx.doi.org/10.3390/antib8040049