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Transcriptomic profiling disclosed the role of DNA methylation and histone modifications in tumor-infiltrating myeloid-derived suppressor cell subsets in colorectal cancer

BACKGROUND: Increased numbers of myeloid-derived suppressor cells (MDSCs) are positively correlated with poor prognosis and reduced survivals of cancer patients. They play central roles in tumor immune evasion and tumor metastasis. However, limited data are available on phenotypic/transcriptomic cha...

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Detalles Bibliográficos
Autores principales: Sasidharan Nair, Varun, Saleh, Reem, Toor, Salman M., Taha, Rowaida Z., Ahmed, Ayman A., Kurer, Mohamed A., Murshed, Khaled, Alajez, Nehad M., Abu Nada, Mohamed, Elkord, Eyad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964037/
https://www.ncbi.nlm.nih.gov/pubmed/31941522
http://dx.doi.org/10.1186/s13148-020-0808-9