Deficiency of Gankyrin in the small intestine is associated with augmented colitis accompanied by altered bacterial composition of intestinal microbiota

BACKGROUND: Gankyrin (GK) is an oncoprotein which regulates inflammatory responses and its inhibition is considered as a possible anti-inflammatory therapy for inflammatory bowel disease (IBD). METHODS: In this study, we investigated the role of GK in epithelial cells using mice with intestinal epit...

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Detalles Bibliográficos
Autores principales: Sakurai, Toshiharu, Nishiyama, Hiroki, Nagai, Tomoyuki, Goto, Susumu, Ogata, Hiroyuki, Kudo, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964040/
https://www.ncbi.nlm.nih.gov/pubmed/31941439
http://dx.doi.org/10.1186/s12876-019-1156-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964040/
https://www.ncbi.nlm.nih.gov/pubmed/31941439
http://dx.doi.org/10.1186/s12876-019-1156-0

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