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The effects of the DNA Demethylating reagent, 5-azacytidine on SMCHD1 genomic localization
BACKGROUND: DNA methylation is an epigenetic modification that mainly repress expression of genes essential during embryogenesis and development. There are key ATPase-dependent enzymes that read or write DNA methylation to remodel chromatin and regulate gene expression. Structural maintenance of chr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964063/ https://www.ncbi.nlm.nih.gov/pubmed/31941450 http://dx.doi.org/10.1186/s12863-020-0809-x |