An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis

Since nuclear envelope breakdown occurs during mitosis in metazoan cells, it has been proposed that macroautophagy must be inhibited to maintain genome integrity. However, repression of macroautophagy during mitosis remains controversial and mechanistic detail limited to the suggestion that CDK1 pho...

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Detalles Bibliográficos
Autores principales: Odle, Richard I., Walker, Simon A., Oxley, David, Kidger, Andrew M., Balmanno, Kathryn, Gilley, Rebecca, Okkenhaug, Hanneke, Florey, Oliver, Ktistakis, Nicholas T., Cook, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964153/
https://www.ncbi.nlm.nih.gov/pubmed/31733992
http://dx.doi.org/10.1016/j.molcel.2019.10.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964153/
https://www.ncbi.nlm.nih.gov/pubmed/31733992
http://dx.doi.org/10.1016/j.molcel.2019.10.016

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