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Insertion of Bacteriorhodopsin Helix C Variants into Biological Membranes
[Image: see text] A peptide corresponding to bacteriorhodopsin (bR) helix C, later named pHLIP, inserts across lipid bilayers as a monomeric α-helix at acidic pH, but is an unstructured surface-bound monomer at neutral pH. As a result of such pH-responsiveness, pHLIP targets acidic tumors and has be...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964287/ https://www.ncbi.nlm.nih.gov/pubmed/31956802 http://dx.doi.org/10.1021/acsomega.9b03126 |