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Derivatives of DANPY (Dialkylaminonaphthylpyridinium), a DNA-Binding Fluorophore: Practical Synthesis of Tricyclic 2-Amino-6-bromonaphthalenes by Bucherer Reaction

[Image: see text] A simple and convergent way to synthesize 2-amino-6-bromonaphthalenes involves condensation of free secondary amines with the corresponding 2-naphthol under Bucherer conditions. The amination protocol relies on common Teflon-capped pressure flasks and has been used to modify the te...

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Detalles Bibliográficos
Autores principales: Kingsbury, Jason S., Elder, Delwin L., Johnson, Lewis E., Smolarski, Brittany A., Zeitler, Hannah E., Armbruster, Emily G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964316/
https://www.ncbi.nlm.nih.gov/pubmed/31956800
http://dx.doi.org/10.1021/acsomega.9b03107