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ASCT2 (SLC1A5)-dependent glutamine uptake is involved in the progression of head and neck squamous cell carcinoma

BACKGROUND: Glutamine is an abundant and versatile nutrient in cancer cells. Head and neck squamous cell carcinoma (HNSCC) was reported to be dependent on mainly glucose, not glutamine, for producing the energy required for survival and proliferation. METHODS: The roles of ASCT2 (SLC1A5) and associa...

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Detalles Bibliográficos
Autores principales: Zhang, Ze, Liu, Ruoyan, Shuai, Yanjie, Huang, Yuting, Jin, Rui, Wang, Xudong, Luo, Jingtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964701/
https://www.ncbi.nlm.nih.gov/pubmed/31819178
http://dx.doi.org/10.1038/s41416-019-0637-9