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Single Eye mRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation

Background: Whether retinal microglia can maintain or restore immune homeostasis during and after inflammation is unclear. We performed single-eye mRNA-sequencing on microglia at different timepoints following a single inflammatory stimulus to characterise their transcriptome during and after resolu...

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Detalles Bibliográficos
Autores principales: Bell, Oliver H., Copland, David A., Ward, Amy, Nicholson, Lindsay B., Lange, Clemens A. K., Chu, Colin J., Dick, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964706/
https://www.ncbi.nlm.nih.gov/pubmed/31993055
http://dx.doi.org/10.3389/fimmu.2019.03033