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Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats

Oxidative stress and neuroinflammation play essential roles in ischemic stroke-induced brain injury. Previous studies have reported that Ezetimibe (Eze) exerts antioxidative stress and anti-inflammatory properties in hepatocytes. In the present study, we investigated the effects of Eze on oxidative...

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Detalles Bibliográficos
Autores principales: Yu, Jing, Wang, Wen-na, Matei, Nathanael, Li, Xue, Pang, Jin-wei, Mo, Jun, Chen, Sheng-pan, Tang, Ji-ping, Yan, Min, Zhang, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964721/
https://www.ncbi.nlm.nih.gov/pubmed/31998437
http://dx.doi.org/10.1155/2020/4717258