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Pan-cancer analysis of somatic mutations and epigenetic alterations in insulated neighbourhood boundaries
Recent evidence shows that the disruption of constitutive insulated neighbourhoods might lead to oncogene dysregulation. We present here a systematic pan-cancer characterisation of the associations between constitutive boundaries and genome alterations in cancer. Specifically, we investigate the enr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964824/ https://www.ncbi.nlm.nih.gov/pubmed/31945090 http://dx.doi.org/10.1371/journal.pone.0227180 |