Sonic Hedgehog upregulation does not enhance the survival and engraftment of stem cell-derived cardiomyocytes in infarcted hearts

The engraftment of human stem cell-derived cardiomyocytes (hSC-CMs) is a promising treatment for remuscularizing the heart wall post-infarction, but it is plagued by low survival of transplanted cells. We hypothesize that this low survival rate is due to continued ischemia within the infarct, and th...

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Detalles Bibliográficos
Autores principales: Weyers, Jill J., Gunaje, Jagadambika J., Van Biber, Benjamin, Martinson, Amy, Reinecke, Hans, Mahoney, William M., Schwartz, Stephen M., Cox, Timothy C., Murry, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964843/
https://www.ncbi.nlm.nih.gov/pubmed/31945113
http://dx.doi.org/10.1371/journal.pone.0227780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964843/
https://www.ncbi.nlm.nih.gov/pubmed/31945113
http://dx.doi.org/10.1371/journal.pone.0227780

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