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Suppression of Superoxide-Hydrogen Peroxide Production at Site I(Q) of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes

Cardiogenic shock following cardiopulmonary resuscitation for sudden cardiac arrest is common, occurring even in the absence of acute coronary artery occlusion, and contributes to high rates of postcardiopulmonary resuscitation mortality. The pathophysiology of this shock is unclear, and effective t...

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Detalles Bibliográficos
Autores principales: Piao, Lin, Fang, Yong-Hu, Hamanaka, Robert B., Mutlu, Gökhan M., Dezfulian, Cameron, Archer, Stephen L., Sharp, Willard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964871/
https://www.ncbi.nlm.nih.gov/pubmed/31939812
http://dx.doi.org/10.1097/CCM.0000000000004095