Cytoplasmic factories, virus assembly, and DNA replication kinetics collectively constrain the formation of poxvirus recombinants

Poxviruses replicate in cytoplasmic structures called factories and each factory begins as a single infecting particle. Sixty-years ago Cairns predicted that this might have effects on vaccinia virus (VACV) recombination because the factories would have to collide and mix their contents to permit re...

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Detalles Bibliográficos
Autores principales: Kieser, Quinten, Noyce, Ryan S., Shenouda, Mira, Lin, Y.-C. James, Evans, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964908/
https://www.ncbi.nlm.nih.gov/pubmed/31945138
http://dx.doi.org/10.1371/journal.pone.0228028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964908/
https://www.ncbi.nlm.nih.gov/pubmed/31945138
http://dx.doi.org/10.1371/journal.pone.0228028

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