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SK2 channels in cerebellar Purkinje cells contribute to excitability modulation in motor-learning–specific memory traces

Neurons store information by changing synaptic input weights. In addition, they can adjust their membrane excitability to alter spike output. Here, we demonstrate a role of such “intrinsic plasticity” in behavioral learning in a mouse model that allows us to detect specific consequences of absent ex...

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Detalles Bibliográficos
Autores principales: Grasselli, Giorgio, Boele, Henk-Jan, Titley, Heather K., Bradford, Nora, van Beers, Lisa, Jay, Lindsey, Beekhof, Gerco C., Busch, Silas E., De Zeeuw, Chris I., Schonewille, Martijn, Hansel, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964916/
https://www.ncbi.nlm.nih.gov/pubmed/31905212
http://dx.doi.org/10.1371/journal.pbio.3000596