Cargando…
SK2 channels in cerebellar Purkinje cells contribute to excitability modulation in motor-learning–specific memory traces
Neurons store information by changing synaptic input weights. In addition, they can adjust their membrane excitability to alter spike output. Here, we demonstrate a role of such “intrinsic plasticity” in behavioral learning in a mouse model that allows us to detect specific consequences of absent ex...
Autores principales: | Grasselli, Giorgio, Boele, Henk-Jan, Titley, Heather K., Bradford, Nora, van Beers, Lisa, Jay, Lindsey, Beekhof, Gerco C., Busch, Silas E., De Zeeuw, Chris I., Schonewille, Martijn, Hansel, Christian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964916/ https://www.ncbi.nlm.nih.gov/pubmed/31905212 http://dx.doi.org/10.1371/journal.pbio.3000596 |
Ejemplares similares
-
Activity of Cerebellar Nuclei Neurons Correlates with ZebrinII Identity of Their Purkinje Cell Afferents
por: Beekhof, Gerrit C., et al.
Publicado: (2021) -
TRPC3 is a major contributor to functional heterogeneity of cerebellar Purkinje cells
por: Wu, Bin, et al.
Publicado: (2019) -
Regular Patterns in Cerebellar Purkinje Cell Simple Spike Trains
por: Shin, Soon-Lim, et al.
Publicado: (2007) -
Lobule-Related Action Potential Shape- and History-Dependent Current Integration in Purkinje Cells of Adult and Developing Mice
por: Beekhof, Gerrit C., et al.
Publicado: (2023) -
Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice
por: Peter, Saša, et al.
Publicado: (2016)