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Isobaric tags for relative and absolute quantitation-based quantitative proteomic analysis of X-linked inhibitor of apoptosis and H2AX in etoposide-induced renal cell carcinoma apoptosis

BACKGROUND: X-linked inhibitor of apoptosis (XIAP) is a vital factor in the anti-apoptosis mechanism of tumors and is highly expressed in renal cell carcinoma (RCC). However, the mechanism through which XIAP regulates DNA damage repair is unknown. This study investigated the regulatory mechanism of...

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Detalles Bibliográficos
Autores principales: Liu, Tian-Shu, Chen, Chao, Zhou, Biao, Xia, Bo-Wen, Chen, Zong-Ping, Yan, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964936/
https://www.ncbi.nlm.nih.gov/pubmed/31855962
http://dx.doi.org/10.1097/CM9.0000000000000553