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Clinico-neuropathological features of isocitrate dehydrogenase 2 gene mutations in lower-grade gliomas
BACKGROUND: Mutations in the isocitrate dehydrogenase 1 (IDH1) and IDH2 genes are important for both the integrated diagnosis and the prognosis of diffuse gliomas. The p.R132H mutation of IDH1 is the most frequently observed IDH mutation, while IDH2 mutations were relatively rarely studied. The aim...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964951/ https://www.ncbi.nlm.nih.gov/pubmed/31833906 http://dx.doi.org/10.1097/CM9.0000000000000565 |