M1 macrophage dependent-p53 regulates the intracellular survival of mycobacteria

Tumor suppressor p53 is not only affects immune responses but also contributes to antibacterial activity. However, its bactericidal function during mycobacterial infection remains unclear. In this study, we found that the p53-deficient macrophages failed to control Mycobacterium tuberculosis (Mtb),...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Yun-Ji, Lee, Junghwan, Choi, Ji-Ae, Cho, Soo-Na, Son, Sang-Hun, Kwon, Sun-Jung, Son, Ji-Woong, Song, Chang-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965052/
https://www.ncbi.nlm.nih.gov/pubmed/31691131
http://dx.doi.org/10.1007/s10495-019-01578-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965052/
https://www.ncbi.nlm.nih.gov/pubmed/31691131
http://dx.doi.org/10.1007/s10495-019-01578-0

Ejemplares similares