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Intracellular Ca(2+) Concentration and Phosphatidylserine Exposure in Healthy Human Erythrocytes in Dependence on in vivo Cell Age

After about 120 days of circulation in the blood stream, erythrocytes are cleared by macrophages in the spleen and the liver. The “eat me” signal of this event is thought to be the translocation of phosphatidylserine from the inner to the outer membrane leaflet due to activation of the scramblase, w...

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Detalles Bibliográficos
Autores principales: Bernhardt, Ingolf, Nguyen, Duc Bach, Wesseling, Mauro C., Kaestner, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965055/
https://www.ncbi.nlm.nih.gov/pubmed/31998145
http://dx.doi.org/10.3389/fphys.2019.01629