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HDAC10 deletion promotes Foxp3(+) T-regulatory cell function

Foxp3(+) T-regulatory (Treg) cells are capable of suppressing immune responses. Lysine acetylation is a key mechanism of post-translational control of various transcription factors, and when acetylated, Foxp3 is stabilized and transcriptionally active. Therefore, understanding the roles of various h...

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Detalles Bibliográficos
Autores principales: Dahiya, Satinder, Beier, Ulf H., Wang, Liqing, Han, Rongxiang, Jiao, Jing, Akimova, Tatiana, Angelin, Alessia, Wallace, Douglas C., Hancock, Wayne W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965082/
https://www.ncbi.nlm.nih.gov/pubmed/31949209
http://dx.doi.org/10.1038/s41598-019-57294-x