Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts

A comprehensive characterization of the lipidome from limited starting material remains very challenging. Here we report a high-sensitivity lipidomics workflow based on nanoflow liquid chromatography and trapped ion mobility spectrometry (TIMS). Taking advantage of parallel accumulation–serial fragm...

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Detalles Bibliográficos
Autores principales: Vasilopoulou, Catherine G., Sulek, Karolina, Brunner, Andreas-David, Meitei, Ningombam Sanjib, Schweiger-Hufnagel, Ulrike, Meyer, Sven W., Barsch, Aiko, Mann, Matthias, Meier, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965134/
https://www.ncbi.nlm.nih.gov/pubmed/31949144
http://dx.doi.org/10.1038/s41467-019-14044-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965134/
https://www.ncbi.nlm.nih.gov/pubmed/31949144
http://dx.doi.org/10.1038/s41467-019-14044-x

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