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Maximizing the ovarian reserve in mice by evading LINE-1 genotoxicity
Female reproductive success critically depends on the size and quality of a finite ovarian reserve. Paradoxically, mammals eliminate up to 80% of the initial oocyte pool through the enigmatic process of fetal oocyte attrition (FOA). Here, we interrogate the striking correlation of FOA with retrotran...
Autores principales: | Tharp, Marla E., Malki, Safia, Bortvin, Alex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965193/ https://www.ncbi.nlm.nih.gov/pubmed/31949138 http://dx.doi.org/10.1038/s41467-019-14055-8 |
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